SCHEMBL15083134

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16288151	1.00	KMT2A (0.37)	KMT2APOLBSMN1; SMN2L3MBTL1FOLH1
	SCHEMBL23565524	0.90	ABCC4 (0.45)	KMT2APOLB
	SCHEMBL15083151	0.88	CASP1 (0.37)	SMN1; SMN2FNTAFNTBACE
	SCHEMBL16288691	0.88	CASP1 (0.37)	SMN1; SMN2FNTAFNTBACE
	SCHEMBL15083256	0.86	KMT2A (0.37)	KMT2APOLBSMN1; SMN2L3MBTL1CYP2C19
	SCHEMBL16287759	0.86	KMT2A (0.37)	KMT2APOLBSMN1; SMN2L3MBTL1CYP2C19
	SCHEMBL3263207	0.84	SMN1; SMN2 (0.48)	SMN1; SMN2FOLH1
	SCHEMBL31133524	0.83	KMT2A (0.42)	KMT2APOLBL3MBTL1FOLH1RIMKLA
	SCHEMBL13146947	0.81	L3MBTL1 (0.43)	KMT2APOLBL3MBTL1FOLH1RIMKLA
	SCHEMBL15083080	0.81	ACE (0.39)	POLBACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.