Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14389506 | 0.83 | KEAP1 (0.50) | KEAP1CA1CA2CA9EGLN1 | |
| SCHEMBL31448014 | 0.82 | KEAP1 (0.62) | KEAP1EGLN1PTPRCCTSLPTPN13 | |
| SCHEMBL13972822 | 0.81 | CA9 (0.49) | CA1CA2CA9BCAT2DDX3X | |
| SCHEMBL14088973 | 0.80 | MAPK1 (0.56) | HIF1A | |
| SCHEMBL27489013 | 0.79 | CA9 (0.73) | CA1CA2CA9BCAT2DDX3X | |
| SCHEMBL12923000 | 0.79 | TSHR (0.56) | CA1CA2CA9 | |
| SCHEMBL91950 | 0.78 | KEAP1 (0.46) | KEAP1CA1CA2CA9EGLN1 | |
| SCHEMBL30289977 | 0.77 | KMT2A (0.65) | KEAP1EGLN1KDM4CKDM4EMAPT | |
| SCHEMBL27450922 | 0.77 | KEAP1 (0.66) | KEAP1EGLN1PTPRCCTSLPTPN13 | |
| SCHEMBL28410063 | 0.77 | KEAP1 (0.50) | KEAP1EGLN1KDM4CKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514449-B1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1997-05-14 | — | — | EP | claimed |
| EP-0514449-A1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN. | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1992-11-25 | — | — | EP | claimed |
| WO-1991012011-A1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1991-08-22 | — | — | WO | claimed |
| EP-0254616-A1 | Process for obtaining novel protein fractions from growth factor preparations, the fractions, and their application as potentiating and stimulating agents, for growth factors | CNRS, Centre National de la Recherche Scientifique (FR) | 1988-01-27 | — | — | EP | claimed |
| WO-1988000207-A1 | METHOD FOR OBTAINING NEW PROTEINIC FRACTIONS FROM GROWTH FACTOR ACTIVITIES, SAID FRACTIONS AND THEIR APPLICATION AS AGENTS FOR THE STIMULATION AND POTENTIALIZATION OF GROWTH FACTOR ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-01-14 | — | — | WO | claimed |
| EP-3914225-A1 | COSMETIC/DERMATOLOGICAL COMPOSITION | Organes Tissus Régénération Réparation Remplacement (FR) | 2021-12-01 | — | — | EP | disclosed |
| EP-3689327-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PULMONARY LESIONS | Organes Tissus Régénération Réparation Remplacement (FR) | 2020-08-05 | — | — | EP | disclosed |
| WO-2020151900-A1 | COSMETIC/DERMATOLOGICAL COMPOSITION | ORGANES TISSUS REGENERATION REPARATION REMPLACEMENT (FR) | 2020-07-30 | — | — | WO | disclosed |
| EP-3685822-A1 | COSMETIC/DERMATOLOGICAL COMPOSITION | Organes Tissus Régénération Réparation Remplacement (FR) | 2020-07-29 | — | — | EP | disclosed |
| EP-2260853-B1 | Biocompatible polymers for a medical composition | ORGANES TISSUS RÉGÉNÉRATION RÉPARATION REMPLACEMENT (FR) | 2015-10-21 | — | — | EP | disclosed |
| EP-2229947-B1 | Biocompatible polymeres for a medicinal preparation | ORGANES TISSUS RÉGÉNÉRATION RÉPARATION REMPLACEMENT (FR) | 2015-07-01 | — | — | EP | disclosed |
| EP-1117695-B1 | BIOCOMPATIBLE POLYMERS, COMPOSITIONS CONTAINING SAME AND THEIR USE FOR THE MANUFACTURE OF DRUGS | BARRITAULT DENIS (FR) | 2015-05-20 | — | — | EP | disclosed |
| EP-0514449-B1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1997-05-14 | — | — | EP | disclosed |
| EP-0514449-A1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN. | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991012011-A1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1991-08-22 | — | — | WO | disclosed |
| WO-1991012011-A1 | NOVEL ANTI-TUMORAL AGENT DERIVED FROM DEXTRAN | THERAPEUTIQUES SUBSTITUTIVES (FR) | 1991-08-22 | — | — | WO | disclosed |
| EP-0254616-A1 | Process for obtaining novel protein fractions from growth factor preparations, the fractions, and their application as potentiating and stimulating agents, for growth factors | CNRS, Centre National de la Recherche Scientifique (FR) | 1988-01-27 | — | — | EP | disclosed |
| EP-0254616-A1 | Process for obtaining novel protein fractions from growth factor preparations, the fractions, and their application as potentiating and stimulating agents, for growth factors | CNRS, Centre National de la Recherche Scientifique (FR) | 1988-01-27 | — | — | EP | disclosed |
| WO-1988000207-A1 | METHOD FOR OBTAINING NEW PROTEINIC FRACTIONS FROM GROWTH FACTOR ACTIVITIES, SAID FRACTIONS AND THEIR APPLICATION AS AGENTS FOR THE STIMULATION AND POTENTIALIZATION OF GROWTH FACTOR ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-01-14 | — | — | WO | disclosed |
| WO-1988000207-A1 | METHOD FOR OBTAINING NEW PROTEINIC FRACTIONS FROM GROWTH FACTOR ACTIVITIES, SAID FRACTIONS AND THEIR APPLICATION AS AGENTS FOR THE STIMULATION AND POTENTIALIZATION OF GROWTH FACTOR ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS (FR) | 1988-01-14 | — | — | WO | disclosed |