Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 0.73 |
| ▸ | CA1 | P00915 | 4/20 | 0.73 |
| ▸ | CA2 | P00918 | 4/20 | 0.73 |
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | DDX3X | O00571 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805191 | 0.85 | CA1 (1.00) | CA9CA1CA2CTSDALDH1A1 | |
| SCHEMBL1127863 | 0.83 | CA1 (0.71) | CA9CA1CA2CTSDALDH1A1 | |
| SCHEMBL14761512 | 0.83 | CA9 (0.71) | CA9CA1CA2CTSDALDH1A1 | |
| SCHEMBL11177249 | 0.81 | CA1 (0.49) | CA9CA1CA2DDX3XBCAT2 | |
| SCHEMBL4805233 | 0.81 | POLB (0.58) | CA9CA1CA2DDX3XBCAT2 | |
| SCHEMBL8609710 | 0.80 | CA1 (0.67) | CA9CA1CA2CTSDALDH1A1 | |
| SCHEMBL13972822 | 0.80 | CA9 (0.49) | CA9CA1CA2DDX3XBCAT2 | |
| SCHEMBL1508326 | 0.79 | KEAP1 (0.54) | CA9CA1CA2DDX3XBCAT2 | |
| SCHEMBL21424612 | 0.79 | CA1 (0.47) | CA9CA1CA2DDX3XALDH1A1 | |
| SCHEMBL239328 | 0.79 | CTSD (0.63) | CA9CA1CA2CTSDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | claimed |
| CN-118852324-A | Albumin binding products of auristatin E derivatives | 拉德克斯公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-111712511-B | Albumin binding products of auristatin E derivatives | 拉德克斯公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-3717503-B1 | ALBUMIN-BINDING PRODRUGS OF AURISTATIN E DERIVATIVES | LADRX CORP (US) | 2023-11-08 | — | — | EP | disclosed |
| US-11377473-B2 | Albumin-binding prodrugs of auristatin E derivatives | CENTURION BIOPHARMA CORPORATION (US) | 2022-07-05 | — | — | US | disclosed |
| CN-1211384-C | Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agent | UPJOHN CO (US) | 2005-07-20 | — | — | CN | disclosed |
| CN-1429108-A | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORP (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1261889-A | Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agent | UPJOHN CO (US) | 2000-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377473-B2 | Albumin-binding prodrugs of auristatin E derivatives | ALB, AURKB, AURKA | CA9 1497/4885CA1 981/4885CA2 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.