Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508332 | 0.78 | PREP (0.39) | ALDH1A1CYP2C19HIF1ACA12CA1 | |
| SCHEMBL6055984 | 0.76 | ESR1 (0.50) | ESR1ESR2CYP3A4ALDH1A1CA12 | |
| SCHEMBL6061648 | 0.76 | ESR1 (0.50) | ESR1ESR2CYP3A4ALDH1A1CA12 | |
| SCHEMBL4235812 | 0.74 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL5990790 | 0.74 | ESR1 (0.56) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL11510565 | 0.74 | ESR2 (0.56) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL1508640 | 0.73 | FFAR1 (0.54) | CYP2C19HIF1AHSD17B10CHRM2CHRM3 | |
| SCHEMBL9319372 | 0.72 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1CYP2C19 | |
| Propionic Acid SCHEMBL3647184 | 0.71 | LMNA (0.67) | ESR1ESR2CYP3A4ALDH1A1ESRRG | |
| Bisphenol A SCHEMBL29514809 | 0.71 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289868-A1 | CARBOXYLIC ACID COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2011-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053974-A1 | CARBOXYLIC ACID COMPOUND | AKR1C3, SLC5A1, GPR119 | ESR1 2912/4885ESR2 2930/4885CYP3A4 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.