Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL405614 | 0.79 | HTT (0.39) | FGFR1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4844097 | 0.69 | PSMB8 (0.38) | LMNAKMT2AL3MBTL1MAT2AKDM4E | |
| SCHEMBL157573 | 0.69 | BIRC5 (0.62) | FGFR1MAT2ABIRC5KDM4EGAA | |
| SCHEMBL27908101 | 0.68 | CYP19A1 (0.54) | KDM4EGAAMAPT | |
| SCHEMBL7986437 | 0.67 | FGFR1 (0.76) | FGFR1MAPK1 | |
| SCHEMBL4275590 | 0.66 | FGFR1 (0.50) | FGFR1MEN1LMNAKMT2ANPC1 | |
| SCHEMBL3406858 | 0.66 | MAPK8 (0.48) | FGFR1MAPK8 | |
| SCHEMBL4557834 | 0.66 | BIRC5 (0.62) | FGFR1MEN1LMNAKMT2AL3MBTL1 | |
| SCHEMBL6480842 | 0.63 | CYP2A6 (0.41) | FGFR1L3MBTL1GAASMN1; SMN2MAPT | |
| SCHEMBL6756590 | 0.63 | FGFR1 (1.00) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |