Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481750 | 0.84 | KMT2A (0.34) | HTTMEN1KMT2APOLBFGFR1 | |
| SCHEMBL4014977 | 0.84 | L3MBTL1 (0.38) | HTTKDM4EATML3MBTL1MEN1 | |
| SCHEMBL6480842 | 0.81 | CYP2A6 (0.41) | HTTL3MBTL1FGFR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4275590 | 0.80 | FGFR1 (0.50) | MEN1NPC1RAB9AKMT2AFGFR1 | |
| SCHEMBL150844 | 0.79 | FGFR1 (0.46) | KDM4EL3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL408242 | 0.74 | BIRC5 (0.38) | HTTKDM4EATML3MBTL1DDB1 | |
| SCHEMBL6308233 | 0.72 | KDM4E (0.45) | HTTKDM4EDDB1CRBNMEN1 | |
| SCHEMBL16720539 | 0.70 | AHR (0.37) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16719930 | 0.69 | CYP17A1 (0.39) | KDM4EPOLBCYP1A2HSD17B10 | |
| SCHEMBL193935 | 0.68 | GPR3 (0.37) | KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903597-A | Compound containing triazine and carbazole structures and organic electroluminescent device | 江苏三月科技股份有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-111689989-B | Containing SO2Polyheterocyclic compounds and uses thereof | 北京燕化集联光电技术有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-111662298-B | Compound containing multiple heterocyclic rings and application thereof in organic electroluminescent device | 北京燕化集联光电技术有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-112521360-A | Arylamine organic compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-111675713-A | Arylamine compound and organic light-emitting device thereof | 长春海谱润斯科技有限公司 | 2020-09-18 | — | — | CN | claimed |
| JP-4769461-B2 | — | — | 2011-09-07 | — | — | JP | claimed |
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | claimed |
| US-20100048513-A1 | Novel inhibitors of chymase | HAWKINS MICHAEL J | 2010-02-25 | — | — | US | claimed |
| US-7648738-B2 | for photopolymerization; photography, relief imaging; color filters | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-19 | — | — | US | claimed |
| EP-1567518-B1 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | claimed |
| US-7459444-B2 | Inhibitors of chymase | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-12-02 | — | — | US | claimed |
| EP-1032709-B1 | METHOD AND APPARATUS FOR PRESERVING HUMAN SALIVA FOR TESTING | SCHNEIDER DAVID R (US) | 2008-06-11 | — | — | EP | claimed |
| US-20060241259-A1 | Oxime ester photoinitiators with heteroaromatic groups | CIBA CORPORATION | 2006-10-26 | — | — | US | claimed |
| JP-2006516246-A | — | — | 2006-06-29 | — | — | JP | claimed |
| EP-1567518-A2 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | Ciba SC Holding AG (CH) | 2005-08-31 | — | — | EP | claimed |
| US-20050176769-A1 | Novel inhibitors of chymase | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-08-11 | — | — | US | claimed |
| WO-2004050653-A2 | OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-06-17 | — | — | WO | claimed |
| EP-0299972-B1 | ANTHELMINTIC QUATERNARYALKYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-03-04 | — | — | EP | claimed |
| EP-0299972-A1 | ANTHELMINTIC QUATERNARYALKYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006132-A1 | ANTHELMINTIC QUATERNARYALKYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048513-A1 | Novel inhibitors of chymase | CMA1, SERPINB1, TPSAB1 | HTT 4560/4885KDM4E 2832/4885ATM 2985/4885 |
| US-20050176769-A1 | Novel inhibitors of chymase | CMA1, SERPINB1, TPSAB1 | HTT 4560/4885KDM4E 2832/4885ATM 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.