Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | NT5E | P21589 | 4/20 | 0.57 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.54 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.54 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15038284 | 0.95 | ADORA1 (0.62) | ADORA1ADORA3NT5EGPR17ADORA2A | |
| SCHEMBL18950170 | 0.94 | ADORA3 (0.65) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL14943009 | 0.89 | NT5E (0.59) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL29185230 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL20901223 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL19442382 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL29511083 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL14853640 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL14929036 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 | |
| SCHEMBL14853619 | 0.88 | GPR17 (0.70) | ADORA1ADORA3NT5EGPR17P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013101690-A1 | MODIFIED MRNAS ENCODING CELL-PENETRATING POLYPEPTIDES | modeRNA Therapeutics (US) | 2013-07-04 | — | — | WO | disclosed |