Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660606 | 0.86 | MET (0.58) | METKDRRETKITPDGFRA | |
| SCHEMBL25362099 | 0.81 | MET (0.48) | METKDRRETKITPDGFRA | |
| SCHEMBL13603260 | 0.80 | PARP10 (0.46) | METKDR | |
| SCHEMBL1137174 | 0.74 | MET (0.48) | METKDRAXL | |
| SCHEMBL17241848 | 0.73 | ALOX5AP (0.43) | METKDRRETKITPDGFRA | |
| SCHEMBL30059265 | 0.72 | MEN1 (0.40) | KITAXL | |
| SCHEMBL25968454 | 0.72 | MEN1 (0.40) | KITAXL | |
| SCHEMBL27171666 | 0.71 | MET (0.49) | METKDRRETKITPDGFRA | |
| SCHEMBL21083204 | 0.71 | KDR (0.57) | METKDRRETKITPDGFRA | |
| SCHEMBL12384981 | 0.70 | MET (0.48) | METKDRRETKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097753-A1 | FUSED HETEROCYCLIC DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2013-07-04 | — | — | WO | disclosed |