Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.43 |
| ▸ | FEN1 | P39748 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 8/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17242344 | 0.84 | ALDH1A1 (0.42) | ALOX5APFEN1SCN9A | |
| SCHEMBL17242219 | 0.84 | ALOX5AP (0.39) | ALOX5APFEN1SCN9A | |
| SCHEMBL1137174 | 0.80 | MET (0.48) | METKDR | |
| SCHEMBL26585989 | 0.78 | ALOX5AP (0.50) | ALOX5APFEN1MAPK14 | |
| SCHEMBL17242347 | 0.76 | SCN9A (0.44) | ALOX5APFEN1SCN9A | |
| SCHEMBL3660606 | 0.74 | MET (0.58) | METRETKITPDGFRAKDR | |
| SCHEMBL15084524 | 0.73 | MET (0.44) | METRETKITPDGFRAKDR | |
| SCHEMBL14290046 | 0.72 | MET (0.46) | METKDR | |
| SCHEMBL27865966 | 0.71 | NPC1 (0.41) | ALOX5APFEN1SCN9A | |
| SCHEMBL17242062 | 0.71 | ROCK2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085482-A | Substituted piperazine compound, and usage method and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2015-11-25 | — | — | CN | disclosed |
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |