Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | AXL | P30530 | 8/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | MST1R | Q04912 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084528 | 0.84 | MET (0.46) | METAXLKDRLMNASMN1; SMN2 | |
| SCHEMBL15084558 | 0.81 | BRD4 (0.39) | METAXLNTRK1FLT4KDR | |
| SCHEMBL15084559 | 0.78 | MET (0.46) | METALDH1A1LMNASMN1; SMN2GSK3B | |
| SCHEMBL15084540 | 0.78 | PDE4B (0.37) | METAXLKDRALDH1A1LMNA | |
| SCHEMBL15084531 | 0.76 | GAA (0.43) | METKDRALDH1A1 | |
| SCHEMBL29827188 | 0.70 | MET (0.49) | METAXLKDRMST1R | |
| SCHEMBL15084519 | 0.70 | MET (0.49) | METAXLKDRMST1R | |
| SCHEMBL30785471 | 0.68 | ALDH1A1 (0.45) | NTRK1FLT4KDRNTRK2ALDH1A1 | |
| SCHEMBL27158307 | 0.68 | ALDH1A1 (0.45) | NTRK1FLT4KDRNTRK2ALDH1A1 | |
| SCHEMBL25670764 | 0.67 | RXFP1 (0.39) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097753-A1 | FUSED HETEROCYCLIC DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2013-07-04 | — | — | WO | disclosed |