Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.67 |
| ▸ | CSF1R | P07333 | 4/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 3/20 | 0.55 |
| ▸ | FLT4 | P35916 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 9/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | RAF1 | P04049 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 2/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | KIF5B | P33176 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547605 | 1.00 | KDM1A (0.67) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| SCHEMBL15084643 | 0.91 | KDR (0.59) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| SCHEMBL2481753 | 0.90 | LCK (0.66) | CSF1RPDGFRBFLT3FLT4LCK | |
| SCHEMBL17278108 | 0.88 | KDM1A (0.73) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| SCHEMBL1015360 | 0.88 | KDM1A (0.66) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| Ammonia Solution, Strong SCHEMBL1010619 | 0.87 | KDM1A (0.65) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| SCHEMBL5177012 | 0.86 | KDM1A (0.64) | KDM1ACSF1RPDGFRBFLT3FLT4 | |
| SCHEMBL14771291 | 0.85 | TRPA1 (0.64) | KDM1AFLT4KDREGFRRAF1 | |
| SCHEMBL14771309 | 0.85 | TRPA1 (0.64) | KDM1AFLT4KDREGFRRAF1 | |
| SCHEMBL30406755 | 0.84 | CSF1R (0.68) | KDM1ACSF1RPDGFRBFLT3FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097753-A1 | FUSED HETEROCYCLIC DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2013-07-04 | — | — | WO | disclosed |