Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.59 |
| ▸ | FLT4 | P35916 | 3/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.55 |
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | KIF5B | P33176 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084644 | 0.91 | KDM1A (0.67) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL20547605 | 0.91 | KDM1A (0.67) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL2481753 | 0.90 | LCK (0.66) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL14771452 | 0.87 | TRPA1 (0.63) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL14771232 | 0.87 | TRPA1 (0.63) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL30406755 | 0.84 | CSF1R (0.68) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL4466873 | 0.84 | CSF1R (0.68) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL30408124 | 0.84 | FLT4 (0.61) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL20547607 | 0.84 | FLT4 (0.61) | KDRFLT4CSF1RPDGFRBFLT3 | |
| SCHEMBL16933076 | 0.83 | KDR (0.62) | KDRFLT4CSF1RPDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013097753-A1 | FUSED HETEROCYCLIC DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2013-07-04 | — | — | WO | disclosed |