SCHEMBL15084704

SCHEMBL15084704

CS(=O)(=O)O[C@@H]1CCN(C(=O)OCc2ccccc2)C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
CYP2C19 P33261 1/20 0.55
F13A1 P00488 4/20 0.50
TGM2 P21980 4/20 0.50
TGM1 P22735 4/20 0.50
HTT P42858 1/20 0.50
PDE4B Q07343 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
GRIN2B Q13224 4/20 0.47
MMP1 P03956 2/20 0.47
MMP3 P08254 2/20 0.47
MMP7 P09237 2/20 0.47
MMP9 P14780 2/20 0.47
MMP13 P45452 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103933 1.00 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL2492947 1.00 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL28408148 0.93 SMN1; SMN2 (0.52) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL21806124 0.93 SMN1; SMN2 (0.52) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL711419 0.93 SMN1; SMN2 (0.52) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL375302 0.93 SMN1; SMN2 (0.64) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL18592896 0.91 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL504558 0.88 SMN1; SMN2 (0.58) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL3620573 0.88 SMN1; SMN2 (0.58) SMN1; SMN2NPC1RAB9ACYP2C19F13A1
SCHEMBL16095295 0.87 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9ACYP2C19F13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333397-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC (US) 2025-10-30 US disclosed
WO-2023034836-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-03-09 WO disclosed
WO-2017186148-A1 NOVEL HETEROCYCLIC COMPOUNDS AS TYROSINE KINASE BCR-ABL INHIBITORS ASTAR BIOTECH LLC (US) 2017-11-02 WO disclosed
EP-2590978-B1 CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY FOB SYNTHESIS INC (US) 2017-09-20 EP disclosed
US-9149461-B2 Carbapenem antibacterials with gram-negative activity FOB SYNTHESIS, INC. (US) 2015-10-06 US disclosed
US-20130172313-A1 Carbapenem Antibacterials with Gram-Negative Activity FOB SYNTHESIS, INC. (US) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333397-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING RBM17, SNRPA, SNRPA1 SMN1; SMN2 301/4885NPC1 1905/4885RAB9A 3354/4885
US-20130172313-A1 Carbapenem Antibacterials with Gram-Negative Activity MGAM, GSK3B, GSK3A SMN1; SMN2 2268/4885NPC1 1620/4885RAB9A 1220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.