Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082515 | 0.85 | MCL1 (0.61) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL15084987 | 0.84 | POLB (0.51) | MEN1KMT2AMCL1ERAP1KDM4E | |
| SCHEMBL12433409 | 0.82 | MCL1 (0.57) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL15082520 | 0.81 | MCL1 (0.57) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL13180136 | 0.81 | MEN1 (0.50) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL7459151 | 0.80 | MCL1 (0.79) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL15082514 | 0.78 | HSD17B3 (0.72) | KMT2AMCL1TDP1ERAP1KDM4E | |
| SCHEMBL3091159 | 0.78 | HSD17B3 (0.63) | MEN1KMT2AMCL1TDP1ERAP1 | |
| SCHEMBL8706410 | 0.77 | MCL1 (0.66) | MEN1KMT2AMCL1KDM4EHPGD | |
| SCHEMBL7459816 | 0.75 | MCL1 (0.56) | MEN1KMT2AMCL1TDP1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9075014-B2 | pH-responsive fluorescent false neurotransmitters and their use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130171664-A1 | PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-07-04 | — | — | US | disclosed |