Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | PON1 | P27169 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702627 | 0.88 | MCL1 (1.00) | MCL1TDP1MEN1KMT2AAKR1B1 | |
| SCHEMBL12433409 | 0.83 | MCL1 (0.57) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15082515 | 0.83 | MCL1 (0.61) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL9277841 | 0.83 | MCL1 (0.77) | MCL1MEN1KMT2AAKR1B1PON1 | |
| SCHEMBL7450481 | 0.83 | MCL1 (0.77) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL3091159 | 0.82 | HSD17B3 (0.63) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15084993 | 0.80 | MEN1 (0.58) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15082520 | 0.80 | MCL1 (0.57) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL7459816 | 0.79 | MCL1 (0.56) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL14473552 | 0.79 | TDP1 (0.56) | MCL1TDP1MEN1KMT2AERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472541-B2 | HALOGENATED- COUMARIN, QUINOLINE-2-ONE, XANTHENE, THIOXANTHENE, SELENOXANTHENEN, OR ANTHRACENE DERIVATIVES; IRRADIATING TO CONTROL THE RELEASE OF THE SOMPOUND SPATIALLY AND TEMPORALLY TO PROBE ITS BIOLOGICAL EFFECTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-10-29 | — | — | US | disclosed |
| EP-1151350-A4 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | UNIV CALIFORNIA (US) | 2002-08-21 | — | — | EP | disclosed |
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-02-07 | — | — | US | disclosed |
| EP-1151350-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | The Regents of the University of California (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000031588-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020016472-A1 | PROTECTING GROUPS WITH INCREASED PHOTOSENSITIVITIES | ERCC4, XPA, GPX4 | MCL1 1400/4885TDP1 793/4885MEN1 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.