Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29369266 | 0.90 | MEN1 (0.50) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15082515 | 0.85 | MCL1 (0.61) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL12433440 | 0.84 | MCL1 (0.54) | MCL1MEN1KMT2AERAP1SLC18A1 | |
| SCHEMBL7459151 | 0.83 | MCL1 (0.79) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15082520 | 0.82 | MCL1 (0.57) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15084993 | 0.82 | MEN1 (0.58) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL15084988 | 0.79 | SLC18A1 (0.50) | MCL1MEN1KMT2AERAP1SLC18A1 | |
| SCHEMBL3091159 | 0.78 | HSD17B3 (0.63) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL14473552 | 0.78 | TDP1 (0.56) | MCL1TDP1MEN1KMT2AERAP1 | |
| SCHEMBL12433414 | 0.76 | HSD17B3 (0.73) | MCL1KMT2AERAP1SLC18A1SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175557-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | UNIVERSITÉ PARIS CITÉ (FR) | 2019-06-13 | — | — | US | disclosed |
| WO-2017216368-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-12-21 | — | — | WO | disclosed |
| US-9075014-B2 | pH-responsive fluorescent false neurotransmitters and their use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130171664-A1 | PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-07-04 | — | — | US | disclosed |
| WO-2011094560-A1 | PH RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175557-A1 | COMPOUNDS USEFUL FOR DECREASING INTERFERON LEVEL | IFNAR1, CXCR4, CXCR3 | MCL1 728/4885TDP1 3695/4885MEN1 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.