SCHEMBL15085181

SCHEMBL15085181

COc1ccc(-n2c(-c3ccccc3)c(-c3ccc(-c4ccc(-c5ccc(C=O)s5)s4)s3)c3ccccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 3/20 0.40
EDNRA P25101 1/20 0.39
APP P05067 1/20 0.39
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
G6PD P11413 1/20 0.38
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MDM4 O15151 1/20 0.37
MDM2 Q00987 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2C19 P33261 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656576 1.00 ALDH1A1 (0.40) ALDH1A1MAPTLMNAEDNRAAPP
SCHEMBL16656236 0.84 APP (0.39) ALDH1A1MAPTLMNAAPPMEN1
SCHEMBL15082778 0.84 APP (0.39) ALDH1A1MAPTLMNAAPPMEN1
SCHEMBL16656574 0.84 MAPT (0.44) ALDH1A1MAPTLMNAEDNRARAB9A
SCHEMBL15085176 0.83 MAPT (0.48) ALDH1A1MAPTLMNAEDNRAAPP
SCHEMBL15085180 0.83 MAPT (0.48) ALDH1A1MAPTLMNAEDNRAAPP
SCHEMBL16656578 0.82 MGAM (0.41) ALDH1A1MAPTLMNAEDNRARAB9A
SCHEMBL16656575 0.78 MAPT (0.47) ALDH1A1MAPTLMNAEDNRARAB9A
SCHEMBL15085177 0.75 MEN1 (0.41) ALDH1A1MAPTEDNRARAB9ANPSR1
SCHEMBL15082767 0.73 MAPT (0.34) ALDH1A1MAPTLMNAAPPNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130167932-A1 INDOLE COMPOUND, AND PHOTOELECTRIC CONVERSION DYE USING SAME, SEMICONDUCTOR ELECTRODE, PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTROCHEMICAL CELL NEC CORPORATION (JP) 2013-07-04 US disclosed