Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15082778 | 1.00 | APP (0.39) | APPIL1R1MAPTKMT2AALDH1A1 | |
| SCHEMBL15085181 | 0.84 | ALDH1A1 (0.40) | APPMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL16656576 | 0.84 | ALDH1A1 (0.40) | APPMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL16656237 | 0.83 | DPP4 (0.42) | IL1R1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL15082768 | 0.83 | MAPT (0.33) | APPIL1R1MAPTKMT2AALDH1A1 | |
| SCHEMBL16656233 | 0.82 | IL1R1 (0.40) | IL1R1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL16656234 | 0.77 | IL1R1 (0.42) | IL1R1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL15082766 | 0.75 | MAPT (0.32) | APPMAPTKMT2AMEN1 | |
| SCHEMBL15082767 | 0.72 | MAPT (0.34) | APPMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL15082779 | 0.71 | IL1R1 (0.48) | IL1R1MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012773-B2 | Thiazole-based compound and uses thereof | NEC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |