SCHEMBL15085233

SCHEMBL15085233

Cc1ccc(/C=N/N(Cc2cccs2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MCL1 Q07820 1/20 0.51
MAPT P10636 5/20 0.49
HSP90AA1 P07900 1/20 0.49
GAA P10253 1/20 0.49
TRPM8 Q7Z2W7 5/20 0.48
PKM P14618 1/20 0.46
POLB P06746 2/20 0.44
LMNA P02545 4/20 0.41
MAPK1 P28482 3/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 3/20 0.40
HPGD P15428 1/20 0.39
CHRM2 P08172 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA2A P08913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139348 0.95 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL12345955 0.95 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL139345 0.88 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL8323484 0.88 ALDH1A1 (0.52) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL19347137 0.87 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL13980002 0.84 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL21564087 0.83 MEN1 (0.44) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL31019595 0.73 MEN1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2MCL1
SCHEMBL13708527 0.73 TRPM8 (0.41) ALDH1A1SMN1; SMN2TRPM8POLBLMNA
SCHEMBL2719503 0.73 TRPM8 (0.67) ALDH1A1SMN1; SMN2TRPM8POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019338-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEM CORP (JP) 2013-07-03 EP disclosed