Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814948 | 0.91 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL69485 | 0.91 | ESR1 (0.59) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL20421308 | 0.85 | ESR1 (0.53) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL505601 | 0.82 | ESR1 (0.65) | ESR1ESR2CYP3A4ALDH1A1SHBG | |
| SCHEMBL10771866 | 0.81 | MMP3 (0.58) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL32675855 | 0.79 | ESR1 (0.62) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL1971090 | 0.78 | KCNN4 (0.48) | ALDH1A1KIF11TSHR | |
| SCHEMBL10865394 | 0.77 | ESR1 (0.46) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL10598204 | 0.77 | ESR1 (0.57) | ESR1ESR2CYP3A4ALDH1A1KIF11 | |
| SCHEMBL10772677 | 0.77 | ESR1 (0.58) | ESR1ESR2CYP3A4KIF11SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019338-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE | MITSUBISHI CHEM CORP (JP) | 2013-07-03 | — | — | EP | disclosed |