Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.77 |
| ▸ | PDE4A | P27815 | 16/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421279 | 0.88 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| Piclamilast SCHEMBL26573 | 0.87 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7421422 | 0.86 | PDE4D (0.79) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7335911 | 0.86 | PDE4D (0.98) | PDE4DPDE4APDE4BPDE4CCYP2B6 | |
| SCHEMBL7418426 | 0.86 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7355660 | 0.85 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL29824395 | 0.85 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7422916 | 0.85 | PDE4D (0.71) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL2888064 | 0.85 | PDE4D (0.77) | PDE4DPDE4APDE4BPDE4CABCB11 | |
| SCHEMBL7422159 | 0.84 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389467-B1 | Therapeutic composition for the regenerative treatment of cartilage diseases | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-07-03 | — | — | EP | disclosed |