Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.77 |
| ▸ | PDE4A | P27815 | 7/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888064 | 1.00 | PDE4D (0.77) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL9229630 | 0.92 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL30084849 | 0.88 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL2889923 | 0.88 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| Piclamilast SCHEMBL26573 | 0.87 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7356144 | 0.87 | PDE4D (0.66) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL7358997 | 0.87 | PDE4D (0.76) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL7335911 | 0.86 | PDE4D (0.98) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL71069 | 0.85 | PDE4B (0.59) | PDE4DPDE4BPDE4APDE4CABCB11 | |
| SCHEMBL15085259 | 0.85 | PDE4D (0.77) | PDE4DPDE4BPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116963773-A | Compositions and methods for treating tumors | 浙江养生堂天然药物研究所有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115397411-A | Pharmaceutical combination and use thereof | 浙江养生堂天然药物研究所有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022156727-A1 | COMPOSITION AND METHOD FOR TREATING TUMORS | 浙江养生堂天然药物研究所有限公司 | 2022-07-28 | — | — | WO | disclosed |