SCHEMBL15085368

SCHEMBL15085368

CC(=O)c1ccc(CCc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.63
KMT2A Q03164 5/20 0.61
ALDH1A1 P00352 3/20 0.59
LMNA P02545 1/20 0.59
RARB P10826 6/20 0.56
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
RARA P10276 1/20 0.53
MTOR P42345 1/20 0.53
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
MMP12 P39900 1/20 0.51
MMP13 P45452 1/20 0.51
P2RX3 P56373 1/20 0.49
PPARA Q07869 1/20 0.49
KDM4E B2RXH2 1/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7825556 0.92 HSD17B10 (0.70) HSD17B10KMT2AALDH1A1LMNARARB
SCHEMBL9818052 0.91 KMT2A (0.73) HSD17B10KMT2ALMNAMAPTMMP12
SCHEMBL70166 0.89 TSHR (0.67) KMT2AALDH1A1RARBMEN1MAPT
Terephthalic Acid SCHEMBL4612225 0.89 TSHR (0.67) KMT2AALDH1A1RARBMEN1MAPT
SCHEMBL2354530 0.87 LMNA (0.77) HSD17B10KMT2AALDH1A1LMNAMAPT
SCHEMBL16864582 0.87 KMT2A (0.83) HSD17B10KMT2AALDH1A1LMNAMEN1
Hydrochloric Acid SCHEMBL7132238 0.86 TSHR (0.63) KMT2AALDH1A1RARBMEN1MAPT
SCHEMBL211540 0.86 TSHR (0.71) KMT2AALDH1A1LMNAMAPTTP53
SCHEMBL14330470 0.84 KMT2A (0.64) HSD17B10KMT2ALMNAMAPTMMP12
Barium SCHEMBL31268595 0.84 TSHR (0.67) KMT2AALDH1A1LMNAMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019338-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEM CORP (JP) 2013-07-03 EP disclosed