SCHEMBL9818052

SCHEMBL9818052

CC(=O)c1ccc(CCc2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.73
HSD17B10 Q99714 1/20 0.67
LMNA P02545 2/20 0.61
MMP12 P39900 1/20 0.53
MMP13 P45452 1/20 0.53
HPGD P15428 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MAPT P10636 2/20 0.52
RAB9A P51151 1/20 0.52
MAOB P27338 5/20 0.50
PYCR1 P32322 1/20 0.50
HSD17B1 P14061 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAOA P21397 1/20 0.48
GAA P10253 1/20 0.48
EPHX2 P34913 1/20 0.47
NR1H4 Q96RI1 1/20 0.47
HDAC1 Q13547 1/20 0.47
PLK1 P53350 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14330470 0.93 KMT2A (0.64) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL2354530 0.91 LMNA (0.77) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL15085228 0.91 HSD17B1 (0.65) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL12243080 0.91 MAOB (0.62) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL15085368 0.91 HSD17B10 (0.63) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL11424105 0.90 HSD17B10 (0.74) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL17457887 0.90 HSD17B10 (0.74) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL12243153 0.89 MAOB (0.64) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL1483217 0.88 KMT2A (0.64) KMT2AHSD17B10LMNAMMP12MMP13
SCHEMBL77965 0.88 KMT2A (0.64) KMT2AHSD17B10LMNAMMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010660-A Method for preparing 1, 2-bis (4-vinyl phenyl) ethane 济南鼎皓医药科技有限公司 2026-05-12 CN disclosed
CN-119263950-A Synthesis method of 1, 2-bis (4-vinyl phenyl) ethane 上海康鹏科技股份有限公司 2025-01-07 CN disclosed
CN-116751127-A Preparation method of 4,4' -diamino bibenzyl 广西茵诺圣药业有限公司 2023-09-15 CN disclosed
EP-3019196-B1 COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2018-06-06 EP disclosed
EP-0275567-B1 NOVEL ORGANIC COMPOUNDS FOR USE IN ELECTROPHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-12-11 EP disclosed
US-4788336-A HEAT AND OXIDATION RESISTANCE EASTMAN KODAK COMPANY (US) 1988-11-29 US disclosed