SCHEMBL15085535

SCHEMBL15085535

Cc1cc(Cl)cc(C(=O)NCC2CC2)c1NC(=O)C1CC(c2cc([N+](=O)[O-])ccc2S(=O)(=O)O)=NN1c1ncccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 3/20 0.34
P2RX7 Q99572 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 4/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MAPT P10636 3/20 0.32
NPC1 O15118 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
RAB9A P51151 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085646 0.93 P2RX7 (0.34) P2RX7L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL15085596 0.92 MALT1 (0.35) MALT1L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL15085544 0.90 P2RX7 (0.35) MALT1P2RX7MAPTKMT2AMAPK1
SCHEMBL15085543 0.89 MALT1 (0.35) MALT1P2RX7ALDH1A1MAPTKMT2A
SCHEMBL15085578 0.89 CNR2 (0.35) MALT1P2RX7ALDH1A1SMN1; SMN2MAPT
SCHEMBL15085562 0.88 MALT1 (0.34) MALT1L3MBTL1ALDH1A1SMN1; SMN2MAPT
SCHEMBL15085620 0.87 MALT1 (0.37) MALT1P2RX7MAPTMAPK1HTT
SCHEMBL15085649 0.86 P2RX7 (0.38) MALT1P2RX7MAPTKMT2AMAPK1
SCHEMBL1148274 0.85 MALT1 (0.35) MALT1P2RX7ALDH1A1SMN1; SMN2MAPT
SCHEMBL15085560 0.85 SMN1; SMN2 (0.32) MALT1L3MBTL1ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed