SCHEMBL15085544

SCHEMBL15085544

Cc1cc(Cl)cc(C(=O)NCC2CC2)c1NC(=O)C1CC(c2cccc(S(=O)(=O)O)c2[N+](=O)[O-])=NN1c1ncccc1Cl

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.35
MALT1 Q9UDY8 4/20 0.34
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
CHRM1 P11229 7/20 0.32
CHRM2 P08172 2/20 0.32
CHRM4 P08173 2/20 0.32
CHRM3 P20309 2/20 0.32
CHRM5 P08912 1/20 0.32
F10 P00742 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085667 0.93 P2RX7 (0.35) P2RX7MALT1CHRM1CHRM2CHRM4
SCHEMBL15085543 0.92 MALT1 (0.35) P2RX7MALT1TP53MAPTCHRM1
SCHEMBL15085542 0.91 MALT1 (0.35) MALT1TP53MAPTKMT2A
SCHEMBL15085535 0.90 MALT1 (0.34) P2RX7MALT1MAPTMAPK1HTT
SCHEMBL15085523 0.89 CNR2 (0.37) P2RX7MALT1MAPTCHRM1CHRM2
SCHEMBL15085620 0.88 MALT1 (0.37) P2RX7MALT1TP53MAPTCHRM1
SCHEMBL15085555 0.88 MALT1 (0.34) MALT1TP53MAPTMAPK1KMT2A
SCHEMBL15085649 0.88 P2RX7 (0.38) P2RX7MALT1TP53MAPTCHRM1
SCHEMBL15085532 0.84 MALT1 (0.32) MALT1TP53MAPT
SCHEMBL15085580 0.84 P2RX7 (0.34) P2RX7MALT1F10CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed