SCHEMBL15085570

SCHEMBL15085570

Cc1cc(Cl)cc(C(=O)NC(C)C2CC2)c1NC(=O)C1CC(c2cccnc2S(=O)(=O)O)=NN1c1ncccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 9/20 0.37
IDO1 P14902 4/20 0.33
NAMPT P43490 2/20 0.32
CCR8 P51685 1/20 0.32
DRD4 P21917 1/20 0.32
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
F10 P00742 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085602 0.93 IDO1 (0.33) MALT1IDO1NAMPTF10
SCHEMBL15085632 0.90 MALT1 (0.37) MALT1IDO1NAMPTCCR8DRD4
SCHEMBL15085588 0.89 MALT1 (0.39) MALT1DRD4TP53MAPT
SCHEMBL15085594 0.89 F10 (0.37) MALT1IDO1NAMPTCCR8F10
SCHEMBL15085583 0.89 MALT1 (0.38) MALT1IDO1CCR8DRD4TP53
SCHEMBL15085555 0.88 MALT1 (0.34) MALT1IDO1TP53MAPT
SCHEMBL15085649 0.87 P2RX7 (0.38) MALT1DRD4TP53MAPT
SCHEMBL15189829 0.87 MALT1 (0.39) MALT1IDO1NAMPTCCR8DRD4
SCHEMBL15085562 0.87 MALT1 (0.34) MALT1IDO1MAPT
SCHEMBL592178 0.87 MALT1 (0.40) MALT1IDO1NAMPTCCR8DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed