SCHEMBL15085588

SCHEMBL15085588

CNC(=O)c1cc(Cl)cc(C)c1NC(=O)C1CC(c2cccnc2S(=O)(=O)O)=NN1c1ncccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 11/20 0.39
GRM4 Q14833 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
DRD4 P21917 1/20 0.31
GRM1 Q13255 1/20 0.30
P2RX7 Q99572 1/20 0.30
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085539 0.92 MALT1 (0.35) MALT1GRM4
SCHEMBL15085649 0.90 P2RX7 (0.38) MALT1TP53MAPTDRD4P2RX7
SCHEMBL15085570 0.89 MALT1 (0.37) MALT1TP53MAPTDRD4
SCHEMBL15085604 0.89 MALT1 (0.38) MALT1GRM4TP53MAPT
SCHEMBL15085590 0.87 MALT1 (0.39) MALT1GRM4TP53MAPTDRD4
SCHEMBL15085542 0.87 MALT1 (0.35) MALT1TP53MAPT
SCHEMBL15085596 0.86 MALT1 (0.35) MALT1TP53MAPT
SCHEMBL9290211 0.85 MALT1 (0.44) MALT1GRM4DRD4P2RX7
SCHEMBL13356325 0.85 MALT1 (0.44) MALT1GRM4DRD4P2RX7
SCHEMBL10119182 0.85 MALT1 (0.46) MALT1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed