SCHEMBL15085577

SCHEMBL15085577

CC(NC(=O)c1cc(Cl)cc(Br)c1NC(=O)C1CC(c2ncccc2S(=O)(=O)O)=NN1c1ncccc1Cl)C1CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
MALT1 Q9UDY8 13/20 0.32
NAMPT P43490 2/20 0.32
F10 P00742 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15085632 0.93 MALT1 (0.37) IDO1MALT1NAMPT
SCHEMBL15085602 0.90 IDO1 (0.33) IDO1MALT1NAMPTF10
SCHEMBL15085581 0.89 MALT1 (0.32) IDO1MALT1
SCHEMBL15085534 0.89 MALT1 (0.31) IDO1MALT1
SCHEMBL15085552 0.89 F10 (0.37) IDO1MALT1NAMPTF10TRPV1
SCHEMBL15085630 0.88 IDO1 (0.33) IDO1MALT1NAMPTF10
SCHEMBL15085530 0.88 ALDH1A1 (0.33) IDO1
SCHEMBL592361 0.87 IDO1 (0.37) IDO1MALT1NAMPTF10
SCHEMBL15085639 0.86 P2RX7 (0.36) MALT1NAMPT
SCHEMBL591565 0.86 MALT1 (0.36) IDO1MALT1NAMPTF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed