Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064995 | 0.88 | GPR119 (0.64) | GPR119KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL15085685 | 0.82 | GPR119 (0.65) | GPR119KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL15085683 | 0.81 | GPR119 (0.49) | GPR119KMT2AMEN1PKMSMN1; SMN2 | |
| SCHEMBL1065715 | 0.81 | GPR119 (0.77) | GPR119 | |
| SCHEMBL15085690 | 0.81 | GPR119 (0.70) | GPR119 | |
| SCHEMBL1083560 | 0.74 | GPR119 (0.69) | GPR119 | |
| SCHEMBL288791 | 0.73 | ROCK1 (0.61) | GPR119ROCK1 | |
| SCHEMBL515793 | 0.72 | GPR119 (0.78) | GPR119ROCK1 | |
| SCHEMBL1066531 | 0.70 | GPR119 (0.68) | GPR119ROCK1 | |
| SCHEMBL13092781 | 0.69 | GPR119 (0.72) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481731-B2 | Compounds, pharmaceutical composition and methods relating thereto | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-09 | — | — | US | disclosed |