Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.65 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13093277 | 0.83 | GPR119 (0.69) | GPR119ROCK1 | |
| SCHEMBL1064995 | 0.83 | GPR119 (0.64) | GPR119ROCK1DRD2MEN1PKM | |
| SCHEMBL15085684 | 0.82 | GPR119 (0.50) | GPR119ROCK1DRD2MEN1PKM | |
| SCHEMBL15085683 | 0.81 | GPR119 (0.49) | GPR119ROCK1DRD2MEN1PKM | |
| SCHEMBL1065716 | 0.79 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12933440 | 0.79 | GPR119 (0.80) | GPR119 | |
| SCHEMBL1083560 | 0.74 | GPR119 (0.69) | GPR119 | |
| SCHEMBL288791 | 0.73 | ROCK1 (0.61) | GPR119ROCK1 | |
| SCHEMBL515122 | 0.72 | GPR119 (0.61) | GPR119ROCK1 | |
| SCHEMBL515155 | 0.72 | GPR119 (0.69) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481731-B2 | Compounds, pharmaceutical composition and methods relating thereto | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-09 | — | — | US | disclosed |