Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23387528 | 0.89 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1PKMKDM4E | |
| SCHEMBL15105447 | 0.89 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1PKMKDM4E | |
| SCHEMBL30611535 | 0.89 | ALDH1A1 (0.43) | KMT2ALMNAALDH1A1PKMKDM4E | |
| SCHEMBL27984878 | 0.86 | GRM8 (0.41) | MEN1KMT2ACYP2C9ALOX15ALDH1A1 | |
| SCHEMBL20837960 | 0.86 | PTPN1 (0.42) | SLC7A5MEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL15129207 | 0.86 | PTPN1 (0.42) | SLC7A5MEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL15105450 | 0.81 | SMN1; SMN2 (0.37) | LMNAALOX15ALDH1A1MAPTPKM | |
| SCHEMBL15085689 | 0.79 | MEN1 (0.48) | SIRT5SLC7A5MEN1KMT2ABLM | |
| SCHEMBL28075885 | 0.79 | MEN1 (0.48) | SIRT5SLC7A5MEN1KMT2ABLM | |
| SCHEMBL31406980 | 0.79 | ALDH1A1 (0.48) | SLC7A5USP2HSD17B10ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11931329-B2 | Compositions and methods for treating anxiety-related disorders | YAMO PHARMACEUTICALS LLC (US) | 2024-03-19 | — | — | US | claimed |
| US-20240024268-A1 | Methods for Dopamine Modulation in Human Neurologic Diseases | SACKNER BERNSTEIN JONATHAN (US) | 2024-01-25 | — | — | US | claimed |
| US-20240016815-A1 | COMPOSITIONS AND METHODS FOR MODULATING CANCER IN NON-HUMAN MAMMALS | HOFFMAN TECHNOLOGIES LLC | 2024-01-18 | — | — | US | claimed |
| US-11806326-B2 | Methods for dopamine modulation in human neurologic diseases | SACKNER BERNSTEIN JONATHAN (US) | 2023-11-07 | — | — | US | claimed |
| US-11786496-B2 | Composition and methods for treating intestinal hyperpermeability | YAMO PHARMACEUTICALS LLC (US) | 2023-10-17 | — | — | US | claimed |
| US-20230141609-A1 | Methods of Treating Amyotrophic Lateral Sclerosis and Symptoms | YAMO PHARMACEUTICALS LLC (US) | 2023-05-11 | — | — | US | claimed |
| US-20230040681-A1 | COMPOSITIONS AND METHODS FOR TREATING ANXIETY-RELATED DISORDERS | YAMO PHARMACEUTICALS LLC (US) | 2023-02-09 | — | — | US | claimed |
| US-11534420-B2 | Compositions and methods for treating cancer | TYME, INC. (US) | 2022-12-27 | — | — | US | claimed |
| CN-115515575-A | Tyrosine derivatives for the modulation of cancer | 迪美公司 | 2022-12-23 | — | — | CN | claimed |
| CN-114901272-A | Sustained release preparation | 霍夫曼技术有限责任公司 | 2022-08-12 | — | — | CN | claimed |
| WO-2015061256-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| WO-2015061288-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME, INC. (US) | 2015-04-30 | — | — | WO | claimed |
| US-20150110735-A1 | HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| US-20150112116-A1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2015-04-23 | — | — | US | claimed |
| US-20150111937-A1 | Compositions and Methods for Treating Intestinal Hyperpermeability | YAMO PHARMACEUTICALS LLC | 2015-04-23 | — | — | US | claimed |
| US-20150111878-A1 | COMPOSITIONS AND METHODS FOR TREATING INTESTINAL HYPERPERMEABILITY | HOFFMAN STEVEN (US) | 2015-04-23 | — | — | US | claimed |
| EP-2804599-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | Tyme, Inc. (US) | 2014-11-26 | — | — | EP | claimed |
| WO-2013109610-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | HOFFMAN STEVEN (US) | 2013-07-25 | — | — | WO | claimed |
| US-20130184214-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-18 | — | — | US | claimed |
| US-8481498-B1 | Pharmaceutical compositions and methods | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2013-07-09 | — | — | US | claimed |