Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30611535 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CASRHSP90AA1HSP90B1GAA | |
| SCHEMBL15105447 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CASRHSP90AA1HSP90B1GAA | |
| SCHEMBL15085695 | 0.89 | SIRT5 (0.41) | ALDH1A1KDM4EPKMKMT2ALMNA | |
| SCHEMBL31406980 | 0.89 | ALDH1A1 (0.48) | ALDH1A1KDM4E | |
| SCHEMBL28837027 | 0.88 | PTPN1 (0.43) | ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL20541058 | 0.88 | PTPN1 (0.43) | ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL15105367 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNA | |
| SCHEMBL30611522 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNA | |
| SCHEMBL23387531 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNA | |
| SCHEMBL15105450 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1HSP90AA1HSP90B1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3655036-B1 | COMPOSITIONS FOR TREATING STRESS-RELATED DISORDERS | HOFFMAN TECH LLC (US) | 2024-09-04 | — | — | EP | claimed |
| CN-116783212-A | Compositions and methods for modulating cancer in non-human mammals | 霍夫曼技术有限责任公司 | 2023-09-19 | — | — | CN | claimed |
| EP-3060200-B1 | TYROSINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM | TYME INC (US) | 2021-05-26 | — | — | EP | claimed |
| CN-116783212-A | Compositions and methods for modulating cancer in non-human mammals | 霍夫曼技术有限责任公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-107835695-B | Compositions and methods for treating autism | 史蒂文·霍夫曼 | 2021-07-09 | — | — | CN | disclosed |