SCHEMBL15086004

SCHEMBL15086004

C=C(Oc1cc(C(C)C)cc(C(C)C)c1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.38
FABP4 P15090 1/20 0.38
MAPT P10636 4/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GLRA1 P23415 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
SLC6A3 Q01959 1/20 0.36
GAA P10253 2/20 0.35
JAK2 O60674 1/20 0.35
USP2 O75604 1/20 0.35
ESR1 P03372 1/20 0.35
ALOX15 P16050 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ESR2 Q92731 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19981468 0.95 KMT2A (0.39) FABP3FABP4MAPTKMT2AMEN1
SCHEMBL498198 0.91 MAPT (0.44) FABP3FABP4MAPTKMT2AMEN1
SCHEMBL15233984 0.82 KMT2A (0.42) KMT2AMEN1GLRA1SMN1; SMN2GAA
SCHEMBL15233880 0.80 KMT2A (0.40) MAPTKMT2ASMN1; SMN2GAALMNA
SCHEMBL2882737 0.78 KMT2A (0.42) MAPTKMT2AMEN1TDP1SMN1; SMN2
SCHEMBL2500899 0.78 MAPT (0.46) MAPTKMT2AMEN1TDP1SMN1; SMN2
SCHEMBL2478197 0.78 MAPT (0.44) MAPTKMT2AMEN1TDP1SMN1; SMN2
SCHEMBL15234181 0.77 ENPP3 (0.39) MAPTKMT2AMEN1SMN1; SMN2ALOX15
SCHEMBL30679620 0.77 MYC (0.42) MAPTKMT2AMEN1SLC6A3ESR1
SCHEMBL2480717 0.76 PDCD1 (0.44) MAPTKMT2AMEN1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373732-B1 PROPYLENE IMPACT COPOLYMER AND METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-03 EP disclosed