Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15086004 | 0.95 | FABP3 (0.38) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL498198 | 0.91 | MAPT (0.44) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL15233880 | 0.82 | KMT2A (0.40) | KMT2AMAPTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL15233984 | 0.80 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL2882737 | 0.78 | KMT2A (0.42) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL2500899 | 0.78 | MAPT (0.46) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL2478197 | 0.78 | MAPT (0.44) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL15233822 | 0.77 | ENPP3 (0.39) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL30679620 | 0.77 | MYC (0.42) | KMT2AMAPTSLC6A3MEN1ESR1 | |
| SCHEMBL2480717 | 0.76 | PDCD1 (0.44) | KMT2AMAPTSMN1; SMN2SLC6A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373702-B1 | PROCATALYST COMPOSITION WITH SUBSTITUTED 1,2-PHENYLENE AROMATIC DIESTER INTERNAL DONOR AND METHOD | GRACE W R & CO (US) | 2018-03-21 | — | — | EP | disclosed |