Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 4/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981091 | 1.00 | LMNA (0.47) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL16473406 | 1.00 | LMNA (0.47) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL16473366 | 0.94 | ALDH1A1 (0.47) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL17193431 | 0.86 | ALDH1A1 (0.49) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL26268067 | 0.85 | ALDH1A1 (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL26269245 | 0.85 | ALDH1A1 (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL11981114 | 0.85 | ALDH1A1 (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL16473421 | 0.83 | LMNA (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL16473381 | 0.83 | LMNA (0.44) | LMNAALDH1A1ALBPOLBADRA1A | |
| SCHEMBL15085979 | 0.82 | TK2 (0.43) | LMNAALDH1A1ALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127280-B2 | Oligonucleotide, and therapeutic agent for dyslipidemia containing oligonucleotide as active ingredient | OSAKA UNIVERSITY (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20130172402-A1 | OLIGONUCLEOTIDE, AND THERAPEUTIC AGENT FOR DYSLIPIDEMIA CONTAINING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT | OSAKA UNIVERSITY (JP) | 2013-07-04 | — | — | US | disclosed |