Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16669851 | 0.81 | KDM4E (0.53) | WEE1KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL15065876 | 0.75 | MIF (0.53) | WEE1KDM4ENPC1ALDH1A1GLA | |
| SCHEMBL15069282 | 0.71 | RAB9A (0.40) | WEE1KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL15069029 | 0.70 | ALDH1A1 (0.59) | WEE1KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL15069026 | 0.68 | NPC1 (0.43) | WEE1KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL25997252 | 0.64 | KDM4E (0.60) | KDM4ENPC1ALDH1A1TP53GLA | |
| SCHEMBL15068889 | 0.64 | KDM4E (0.57) | KDM4ENPC1ALDH1A1TP53GLA | |
| SCHEMBL21301263 | 0.64 | KDM4E (0.57) | KDM4ENPC1ALDH1A1TP53GLA | |
| SCHEMBL15086147 | 0.64 | KDM4E (0.54) | KDM4ENPC1ALDH1A1TP53GLA | |
| SCHEMBL21301196 | 0.62 | CA12 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013101974-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |