Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20479319 | 0.86 | AKT1 (0.44) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL14704751 | 0.81 | AKT1 (0.48) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL13664871 | 0.80 | AKT1 (0.52) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL3104098 | 0.74 | AKT1 (0.43) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL25698474 | 0.73 | AKT1 (0.45) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL25698477 | 0.73 | AKT1 (0.45) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL1953466 | 0.73 | OPRM1 (0.44) | CA12ALDH1A1 | |
| SCHEMBL14737847 | 0.72 | SYK (0.56) | IDO1NPFFR1NPFFR2CTSSCTSL | |
| SCHEMBL25698468 | 0.72 | AKT1 (0.44) | AKT1IDO1NPFFR1NPFFR2CTSS | |
| SCHEMBL25572358 | 0.72 | AKT1 (0.44) | AKT1IDO1NPFFR1NPFFR2CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |