Ethylene Glycol

Ethylene Glycol

SCHEMBL1508679

C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCc1ccccc1Oc1ccccc1CCCCCCCC.OCCO

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.57
THRB P10828 1/20 0.57
LIPG Q9Y5X9 1/20 0.51
ALOX5 P09917 1/20 0.50
PTGS2 P35354 1/20 0.50
PPARA Q07869 2/20 0.48
PPARG P37231 1/20 0.46
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL11666399 1.00 THRA (0.57) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL11057177 1.00 THRA (0.57) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL21373973 1.00 THRA (0.57) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL11667182 1.00 THRA (0.57) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL2169345 1.00 THRA (0.57) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL487727 0.97 THRA (0.56) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL3259231 0.97 THRA (0.56) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL20582190 0.97 THRA (0.56) THRATHRBLIPGALOX5PTGS2
Ethylene Glycol SCHEMBL11574529 0.97 THRA (0.56) THRATHRBLIPGALOX5PTGS2
Ethylene SCHEMBL4621010 0.93 THRA (0.59) THRATHRBLIPGALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3463317-A1 METHOD FOR PREPARATION OF QUICK DISSOLVING THIN FILMS CONTAINING BIOACTIVE MATERIAL WITH ENHANCED THERMAL STABILITY Aridis Pharmaceuticals, Inc. (US) 2019-04-10 EP claimed
WO-2017214187-A1 METHOD FOR PREPARATION OF QUICK DISSOLVING THIN FILMS CONTAINING BIOACTIVE MATERIAL WITH ENHANCED THERMAL STABILITY ARIDIS PHARMACEUTICALS, INC. (US) 2017-12-14 WO claimed
US-20140356396-A1 ROTAVIRUS PREPARATIONS WITH EXCESS CALCIUM IONS AND HIGH VISCOSITIES THAT ENSURE VIABILITY AT ELEVATED TEMPERATURES PULLIAM BRIAN L (US) 2014-12-04 US claimed
EP-2747777-A2 ROTAVIRUS PREPARATIONS WITH EXCESS CALCIUM IONS AND HIGH VISCOSITIES THAT ENSURE VACCINE VIABILITY AT ELEVATED TEMPERATURES Pulliam, Brian (US) 2014-07-02 EP claimed
EP-2197283-B1 FORMULATIONS FOR PRESERVATION OF ROTA VIRUS ARIDIS PHARMACEUTICALS (US) 2013-07-17 EP claimed
WO-2013029033-A2 ROTAVIRUS PREPARATIONS WITH EXCESS CALCIUM IONS AND HIGH VISCOSITIES THAT ENSURE VACCINE VIABILITY AT ELEVATED TEMPERATURES PULLIAM BRIAN (US) 2013-02-28 WO claimed
US-8241886-B2 Formulations for preservation of rotavirus ARIDIS PHARMACEUTICALS (US) 2012-08-14 US claimed
US-20100226939-A1 FORMULATIONS FOR PRESERVATION OF ROTAVIRUS STREETERVILLE CAPITAL, LLC 2010-09-09 US claimed
EP-2197283-A2 FORMULATIONS FOR PRESERVATION OF ROTA VIRUS Aridis Pharmaceuticals (US) 2010-06-23 EP claimed
WO-2009042202-A2 FORMULATIONS FOR PRESERVATION OF ROTA VIRUS ARIDIS PHARMACEUTICALS (US) 2009-04-02 WO claimed
EP-2029095-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'Oréal (FR) 2009-03-04 EP claimed
WO-2007135297-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2007-11-29 WO claimed
US-11633472-B2 Compositions GLAXOSMITHKLINE BIOLOGICALS SA 2023-04-25 US disclosed
US-20230017661-A1 COMPOSITIONS AND MODULAR NANO- AND MICROPARTICLES FOR THE DELIVERY OF VARIOUS AGENTS AND USE THEREOF VERI NANO INC. (US) 2023-01-19 US disclosed
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2022-08-02 US disclosed
US-20210322537-A1 Method For Preparation of Quick Dissolving Thin Films Containing Bioactive Material With Enhanced Thermal Stability STREETERVILLE CAPITAL, LLC 2021-10-21 US disclosed
WO-1996032124-A1 MODIFIED LYSINE OR ARGININE CONTAINING PROTEINS AND PEPTIDES NEW YORK BLOOD CENTER (US) 1996-10-17 WO disclosed
US-5547833-A Radial flow assay, delivering member, test kit, and methods INTRACEL CORPORATION (US) 1996-08-20 US disclosed
WO-1995018970-A1 RADIAL FLOW ASSAY INTRACEL CORPORATION (US) 1995-07-13 WO disclosed
US-5384128-A Method of and compounds for treatment for cystic fibrosis UNIVERSITY OF ALABAMA RESEARCH FOUNDATION (US) 1995-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents KRT18, KRTCAP2, TUBB4A THRA 3388/4885THRB 4285/4885LIPG 4336/4885
US-20230017661-A1 COMPOSITIONS AND MODULAR NANO- AND MICROPARTICLES FOR THE DELIVERY OF VARIOUS AGENTS AND USE THEREOF CD47, CD44, CHMP4B THRA 3837/4885THRB 4573/4885LIPG 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.