SCHEMBL15087397

SCHEMBL15087397

CCCC[C@H](COC(N)=O)[C@@H](OC(N)=O)c1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP2D6 P10635 1/20 0.38
PKM P14618 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 3/20 0.35
CA2 P00918 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CTSK P43235 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15078592 0.82 MEN1 (0.35) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL10119765 0.82 MEN1 (0.37) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL3435208 0.82 MEN1 (0.37) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL3435194 0.82 MEN1 (0.37) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL15078518 0.78 MEN1 (0.34) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL15078569 0.78 MEN1 (0.34) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL15078560 0.78 MEN1 (0.34) SMN1; SMN2ALDH1A1CA2CYP3A4MEN1
SCHEMBL18567952 0.76 MEN1 (0.35) ALDH1A1MEN1KMT2ACTSKHPGD
SCHEMBL3435773 0.74 TAS1R3 (0.37) CYP2D6ALDH1A1CYP3A4MAPK1LMNA
SCHEMBL19254737 0.74 TAS1R3 (0.37) CYP2D6ALDH1A1CYP3A4MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100566-A1 Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed