SCHEMBL19254737

SCHEMBL19254737

CC[C@H](O)C(OC(N)=O)c1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
HSD17B10 Q99714 2/20 0.36
CASP1 P29466 1/20 0.35
ADRA2A P08913 2/20 0.34
MAPK1 P28482 2/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
MAOA P21397 1/20 0.34
ADRA1D P25100 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3435926 1.00 TAS1R3 (0.37) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL3435773 1.00 TAS1R3 (0.37) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL3435771 1.00 TAS1R3 (0.37) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL18567620 0.91 CASP1 (0.35) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL10119765 0.87 MEN1 (0.37) KMT2AMEN1HSD17B10CYP3A4ALDH1A1
SCHEMBL3435208 0.87 MEN1 (0.37) KMT2AMEN1HSD17B10CYP3A4ALDH1A1
SCHEMBL3435194 0.87 MEN1 (0.37) KMT2AMEN1HSD17B10CYP3A4ALDH1A1
SCHEMBL15078590 0.86 TAS1R3 (0.36) TAS1R3TAS1R1TAS1R2KMT2AMEN1
SCHEMBL3437319 0.84 CXCL8 (0.36) KMT2AMEN1LMNACYP3A4CYP2D6
SCHEMBL19254736 0.84 CXCL8 (0.36) KMT2AMEN1LMNACYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed