Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.30 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508993 | 0.83 | — | — | |
| SCHEMBL1508995 | 0.83 | — | — | |
| SCHEMBL14802189 | 0.79 | — | — | |
| SCHEMBL2490403 | 0.79 | — | — | |
| SCHEMBL1508660 | 0.78 | RORC (0.37) | RORCGPR119 | |
| SCHEMBL1508767 | 0.77 | — | — | |
| SCHEMBL1509094 | 0.74 | HSD17B10 (0.46) | — | |
| SCHEMBL2527201 | 0.74 | — | — | |
| SCHEMBL1509084 | 0.74 | HSD17B10 (0.46) | — | |
| SCHEMBL1509097 | 0.74 | CYP1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |