Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625280 | 0.81 | RORC (0.43) | RORCGPR119USP30CKS1BSKP1 | |
| SCHEMBL25065819 | 0.80 | KLK7 (0.42) | RORCMEN1KMT2AABCB1NR1H2 | |
| SCHEMBL1508765 | 0.78 | RORC (0.31) | RORCGPR119 | |
| SCHEMBL3430518 | 0.78 | HSD17B10 (0.39) | RORC | |
| SCHEMBL15718905 | 0.78 | HSD17B10 (0.39) | RORC | |
| SCHEMBL18094055 | 0.78 | HSD17B10 (0.39) | RORC | |
| SCHEMBL17176563 | 0.75 | UCHL1 (0.45) | RORCGPR119ABCB1HTRA1UCHL1 | |
| SCHEMBL1509057 | 0.75 | NR1H2 (0.36) | RORCGPR119ABCB1CKS1BSKP1 | |
| SCHEMBL26453413 | 0.75 | UCHL1 (0.45) | RORCGPR119ABCB1HTRA1UCHL1 | |
| SCHEMBL31391867 | 0.75 | APLNR (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |