Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10191049 | 0.89 | BRD4 (0.45) | GRIN1GRIN2AGRIN2BBRD4POLB | |
| SCHEMBL15076060 | 0.88 | BRD4 (0.45) | GRIN1GRIN2AGRIN2BBRD4POLB | |
| SCHEMBL14129352 | 0.81 | BRD4 (0.47) | BRD4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10191056 | 0.80 | NAAA (0.52) | POLBMEN1KMT2ANAAANPC1 | |
| SCHEMBL14129503 | 0.77 | SMN1; SMN2 (0.45) | BRD4NAMPTMEN1KMT2AHDAC1 | |
| SCHEMBL14129348 | 0.76 | SMN1; SMN2 (0.47) | BRD4NAMPTMEN1KMT2AHDAC1 | |
| SCHEMBL16510003 | 0.76 | SMN1; SMN2 (0.47) | BRD4NAMPTMEN1KMT2AHDAC1 | |
| SCHEMBL12173390 | 0.76 | BRD4 (0.46) | BRD4POLBNPC1RAB9A | |
| SCHEMBL10191159 | 0.76 | BRD4 (0.42) | BRD4POLBNAMPT | |
| SCHEMBL16360963 | 0.76 | HDAC1 (0.41) | POLBNAMPTHDAC1HDAC2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991273-B1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | LIFE TECHNOLOGIES CORP (US) | 2013-07-03 | — | — | EP | disclosed |