Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8738314 | 0.89 | HPGD (0.66) | HPGDMMP1MAPK14MMP2CA12 | |
| SCHEMBL3377096 | 0.85 | NPC1 (0.66) | HPGDLMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL8507006 | 0.85 | NPC1 (0.66) | HPGDLMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL8506869 | 0.85 | NPC1 (0.66) | HPGDLMNASMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL5856056 | 0.83 | ALDH1A1 (0.68) | HPGDCA1CA2LMNASMN1; SMN2 | |
| SCHEMBL15090036 | 0.83 | NPC1 (0.65) | HPGDMMP13SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL15087731 | 0.83 | NPC1 (0.65) | HPGDMMP13SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL16373032 | 0.83 | NPC1 (0.65) | HPGDMMP13SMN1; SMN2ALDH1A1EPHX2 | |
| SCHEMBL19113064 | 0.81 | HPGD (0.55) | HPGDMMP1MAPK14MMP2CA12 | |
| SCHEMBL13754242 | 0.81 | HPGD (0.66) | HPGDMMP1MAPK14MMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |