Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.34 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.34 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.34 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108279 | 0.84 | ALDH1A1 (0.37) | AAK1KMOSREBF2MAPTKDM4E | |
| SCHEMBL1097848 | 0.81 | AAK1 (0.34) | AAK1KMONPC1SREBF2MAPT | |
| SCHEMBL1097565 | 0.81 | GAA (0.31) | — | |
| SCHEMBL15087871 | 0.75 | DPP4 (0.44) | CYP1A2CYP2E1CYP2D6CYP2A6CYP2C9 | |
| SCHEMBL15087883 | 0.75 | DAO (0.37) | AAK1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL15577810 | 0.75 | DYRK1A (0.46) | DYRK1ACLK4DYRK1BCLK1CLK2 | |
| SCHEMBL15087879 | 0.73 | DYRK1A (0.44) | DYRK1ACLK4DYRK1BCLK1KMO | |
| SCHEMBL1098764 | 0.71 | CYP2A6 (0.34) | AAK1CYP2A6KMOMEN1KMT2A | |
| SCHEMBL24638508 | 0.70 | IKBKE (0.38) | AAK1KMONPC1MAPTMEN1 | |
| SCHEMBL27111217 | 0.70 | MAPT (0.47) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172338-A1 | OXYGEN LINKED PYRIMIDINE DERIVATIVES | CELL THERAPEUTICS, INC. (US) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172338-A1 | OXYGEN LINKED PYRIMIDINE DERIVATIVES | DPYD, TK2, TK1 | AAK1 996/4885CYP1A1 2156/4885CYP1A2 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.