SCHEMBL1508849

SCHEMBL1508849

C=C(C)C(=O)OC(C)[Si](O[Si](OC)(OC)OC)(O[Si](OC)(OC)OC)O[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193159 0.85 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL16537575 0.76 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL6925919 0.76 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL9560048 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL9559905 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL1253678 0.73 TSHR (0.41) ALDH1A1TSHR
SCHEMBL145421 0.72 TSHR (0.43) ALDH1A1TSHR
SCHEMBL3886364 0.72 TSHR (0.43) ALDH1A1TSHR
SCHEMBL16538069 0.71 TSHR (0.40) ALDH1A1TSHR
SCHEMBL8749909 0.71 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110151000-A1 NITRIC OXIDE-RELEASING COMPOSITIONS, DEVICES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2011-06-23 US disclosed
EP-2288343-A1 NITRIC OXIDE-RELEASING COMPOSITIONS, DEVICES AND METHODS 3M Innovative Properties Company (US) 2011-03-02 EP disclosed
WO-2009131931-A1 NITRIC OXIDE-RELEASING COMPOSITIONS, DEVICES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-10-29 WO disclosed