SCHEMBL15088930

SCHEMBL15088930

Cc1cccc(N2c3cc4c(cc3-c3ccc(-c5ccccn5)c5cccc2c35)c2cc(-c3ccccn3)ccc2n4-c2cccc(C)c2)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.33
POLB P06746 1/20 0.33
NPY5R Q15761 1/20 0.32
MAPK14 Q16539 1/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32
TUBB2B Q9BVA1 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089177 0.92 MAPK14 (0.35) NPY5RMAPK14HTR1AHTR7
SCHEMBL15089200 0.90 GRM5 (0.36) GRM5MAPK14HTR1AHTR7
SCHEMBL15088913 0.90 GRM5 (0.34) GRM5POLBNPY5RMAPK14KMT2A
SCHEMBL15089196 0.90 MAPK14 (0.34) GRM5NPY5RMAPK14L3MBTL1HTR1A
SCHEMBL15089175 0.89 HTR1A (0.34) GRM5NPY5RMAPK14L3MBTL1HTR1A
SCHEMBL15088836 0.88 GRM5 (0.33) GRM5POLBNPY5RKMT2AL3MBTL1
SCHEMBL15089219 0.87 MAPK14 (0.36) NPY5RMAPK14HTR1AHTR7
SCHEMBL15089211 0.86 MAPK14 (0.33) GRM5MAPK14HTR1AHTR7
SCHEMBL15089176 0.85 GRM5 (0.35) GRM5MAPK14HTR1AHTR7
SCHEMBL15088934 0.84 PDK2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed