SCHEMBL15088979

SCHEMBL15088979

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1ccncc1)c1cccc2cccc-3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PDE6D O43924 1/20 0.36
PGR P06401 8/20 0.33
APP P05067 2/20 0.32
MAPT P10636 2/20 0.32
SNCA P37840 2/20 0.32
NSD2 O96028 1/20 0.32
GAA P10253 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
MAPK1 P28482 1/20 0.31
MEN1 O00255 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088985 0.91 PDE6D (0.41) ALDH1A1KDM4EHPGDPDE6DPGR
SCHEMBL15089007 0.88 HSD17B10 (0.44) ALDH1A1KDM4EHPGDPDE6DPGR
SCHEMBL15088990 0.86 PDE6D (0.52) ALDH1A1PDE6DPGRMEN1KMT2A
SCHEMBL15089213 0.84 KDM4E (0.40) ALDH1A1KDM4EHPGDSMN1; SMN2PDE6D
SCHEMBL15088980 0.83 PDE6D (0.43) ALDH1A1PDE6DPGRMEN1KMT2A
SCHEMBL15089088 0.83 PDE6D (0.43) PDE6DPGRMEN1KMT2A
SCHEMBL15089004 0.83 KDM4E (0.45) ALDH1A1KDM4EHPGDSMN1; SMN2PDE6D
SCHEMBL15088992 0.83 PDE6D (0.36) KDM4EPDE6DPGRMAPTMAPK1
SCHEMBL15089064 0.82 PDE6D (0.39) PDE6DPGR
SCHEMBL15088999 0.81 HTR2C (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed