SCHEMBL15088992

SCHEMBL15088992

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1ccc(-n2c4ccccc4c4ccccc42)cc1)c1cccc2cccc-3c12

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.36
KDM4E B2RXH2 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
PGR P06401 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088991 0.93 PGR (0.33) PDE6DKDM4EATML3MBTL1MEN1
SCHEMBL15088981 0.89 PDE6D (0.35) PDE6DKDM4EATML3MBTL1PGR
SCHEMBL15088993 0.88
SCHEMBL15088985 0.87 PDE6D (0.41) PDE6DKDM4EATML3MBTL1MEN1
SCHEMBL15088983 0.86 KDM4E (0.30) PDE6DKDM4EMEN1MAPTMAPK1
SCHEMBL15089181 0.86 PDE6D (0.37) PDE6DKDM4EATML3MBTL1MEN1
SCHEMBL15088990 0.85 PDE6D (0.52) PDE6DMEN1KMT2APGR
SCHEMBL18810852 0.83 KDM4E (0.31) PDE6DKDM4EATML3MBTL1
SCHEMBL15088984 0.83 PDE6D (0.33) PDE6D
SCHEMBL15088829 0.83 PDE6D (0.35) PDE6DKDM4EATML3MBTL1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed